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The objective of the proposed study is to test the hypothesis that planktonic and benthic trophic dynamics and benthic-pelagic coupling control the speciation, transport, bioavailability, bioaccumulation and toxic effects for synthetic organic contaminants in Chesapeake Bay. We propose to develop a numerical simulation model of the key ecological processes: to integrate data collected by various investigators in the Bay region; to test hypothesis about interactions between trophic dynamics and contaminant fate/effects; and to provide information needed for Ecological Risk Assessment.