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We will investigate temperature/salinity tolerance for larvae of the freshwater bivalve mollusc Dreissena polymorpha using a temperature/salinity matrix which encompasses the northern Chesapeake Bay during the spawning season. Results of survival and growth observations will be entered in a stepwise multiple regression equation which will be used to generate predictive response surfaces relating growth and survival to salinity/temperature combinations. Investigations will also be made into the contributions made by individual electrolytes to salinity stress in Dreissena larvae. A comprehensive study will also be made of the sodium regulatory mechanism in Dreissena larvae.