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We propose to examine how dissolved oxygen concentrations and the spatial patterning of dissolved oxygen, water temperature and predation and prey abundances interact to affect the consumption, growth, production and recruitment of important fishes in the Chesapeake Bay. Research will focus on key piscivores (striped bass, bluefish, weakfish) and planktivores (Atlantic menhaden, bay anchovy). Spatially-explicit models will be used to compare patterns of growth and consumption relative to changes in habitat structure, prey abundances and spatial heterogeneity in the environment. Model simulations will address specific management questions dealing with the interrelationships of fish production and water quality.