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R/BT-05
Red drum growth hormone: Heterologous production in a eukaryotic expression system, physiology, and effects on growth after dietary administration
Principal Investigator:
John J. TrantStart/End Year:
1996 - 2001Institution:
Center of Marine Biotechnology, University of Maryland Biotechnology InstituteTopic(s):
Description:
To evaluate several biotechnology approaches for producing biologically active recombinant red drum growth hormone (GH), to understand the physiology of GH secretion and the possible functions of GH in red drum, and to determine whether feeding the recombinant hormone in the diet is an effective method for administering GH and promoting growth of fish. Long-term goals are to develop techniques for mass producing piscine recombinant growth hormones inexpensively, to undertake a comprehensive investigation of the functions of GH using the recombinant hormone, as well as developing a practical method for administering them to fish at commercial aquaculture facilities to enhance fish growth.
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Featured Fellow
Leone Yisrael is a cephalopod-loving scuba diver, cook, and loves to try new activities. She conducts genetic analysis and fieldwork at the Smithsonian Environmental Research Center through the Coastal Disease Ecology Lab.
Featured Research Project
Developing a habitat model for mysids, an important link in Chesapeake Bay food webs
Mysids are important mesozooplankton prey for many species of fish in Chesapeake Bay and are an important link in transferring energy from lower to upper trophic levels. Mysids also serve as biological vectors for benthic-pelagic coupling due to their diel vertical migration and omnivorous prey-switching behavior, which makes mysids important regulators of food web architecture. Despite their central role in coastal food webs, surprisingly little is known about mysid ecology and dynamics in Chesapeake Bay.
